FULFILLING GLOBAL MEDICAL NEEDS

SUPERBUGS AND GROWING ANTIBIOTIC RESISTANCE

The technology incorporated into the W250 machine has been shown to be capable of addressing even serious wound infection, including from antibiotic resistant bacteria ‘superbugs’.

Common superbugs include Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant Enterococcus (VRE), Carbapenem-resistant Enterobacteriaceae (CRE) and multidrug-resistant (MDR) Pseudomonas aeruginosa.

Even after several decades of use of silver in medical dressings and topical creams, there is either none, or very little evidence of resistance of bacteria to electrically generated silver ions.

Together with the established effects on microorgansisms of low intensity (amperage) direct current (LIDC) generated by the SIS machines, and the potential dielectrophoretic effects of silver cations on infected cells, the concept of ‘drug resistance’ will probably never apply with use of the SIS technology.

DRUG DELIVERY PROBLEMS

Inflammation and/or small blood vessel (arteriole) neurological vasoconstriction often exist in areas of infections and chronic wounds, restricting medicine delivery and uptake. There are also many hard-to-reach locations of infections, due to the body’s natural anatomical compartments and barriers—from large to microscopic scale.

Silver iontophoresis and low intensity direct current (LIDC) effects do not depend on blood flow. The direct constant-current silver cation delivery and LIDC generated by the SIS machines, operating on the basic physics of electric voltage and current, targets the infection via the shortest possible conductive route through the body.

ANTIBIOTICS AND ANTIVIRALS OVERDOSING PROBLEMS

To reach localized infections, especially in peripheries of the body, the entire body has to be unnecessarily loaded with antibiotics or antiviral drugs.

The M250 model SIS machine operates with low intensity direct current (LIDC), calibrated with extreme precision to the SIS electrodes; only the minimum necessary LIDC is delivered, directly to the targeted infected area.

ANTIBIOTICS SIDE EFFECTS AND REACTIONS INCREASING

Digestive system disruption: vomiting, nausea, diarrhoea, bloating and indigestion, abdominal pain, loss of appetite.

Allergic reactions: itchy skin rashes (hives), coughing, wheezing, tightness of the throat and breathing difficulties—needing more drugs to suppress.

Possible life-threatening allergic reaction (anaphylaxis): multiple symptoms including swelling and tightening of the neck, drop in blood pressure and loss of consciousness.

Risks of severe long-term nerve damage (peripheral neuropathy): from Fluoroquinolone antibiotics—Levaquin (levofloxacin), Cipro (ciprofloxacin), Avelox (moxifloxacin), Noroxin (norfloxacin), Floxin (ofloxacin) and Factive (gemifloxacin).

Non-invasive silver iontophoresis and low intensity direct current (LIDC) have none of these drug side effects or risks.

SPECTRUM OF ACTIVITY

Antibiotics are classed as either narrow or broad spectrum, based on the range of bacterial species susceptible to these drugs.

Electrically generated silver ions are super-broad spectrum agents, for both gram-negative and gram-positive type bacteria; low intensity direct current (LIDC) is effective for entire species of infecting microorganisms.

NO OR FEW DRUGS FOR VIRUSES WITH MAJOR SIDE EFFECTS AND RISKS

Only a small number of drugs exist for the treatment of some viral infections. These drugs can have many side effects, including organ failure, cardiac arrest, psychological disturbances, and confirmed fatalities. Drug delivery is also limited by the same uptake and overdosing problems of antibiotics (read above). The newer ‘direct-acting’ antiviral drugs for hepatitis treatment carry the highest category USA Food and Drug Administration (FDA) ‘black box’ warnings due to lethal side-effects.

The SIS equipment can be applied for the treatment of most viral infections. Electrically generated silver ions have been shown to be effective against many viruses, including the Human Herpes, Influenza (flu) and Adenoviridae families of viruses, and to inhibit the Hepatitis B virus and the HIV-1 virus. Low intensity direct current (LIDC) itself is effective for entire species of infecting microorganisms, and has no drug side effects or risks.

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